Characterization of sputum biomarkers for asthma–COPD overlap syndrome [Erratum]

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Characterization of sputum biomarkers for asthma–COPD overlap syndrome [Erratum]

[This corrects the article on p. 2457 in vol. 11, PMID: 27757028.].

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Characterization of sputum biomarkers for asthma–COPD overlap syndrome

Asthma-COPD overlap syndrome (ACOS) is a commonly encountered chronic airway disease. However, ACOS is still a consensus-based clinical phenotype and the underlying inflammatory mechanisms are inadequately characterized. To clarify the inflammatory mediatypical for ACOS, five biomarkers, namely interleukin (IL)-13, myeloperoxidase (MPO), neutrophil gelatinase-associated lipocalin (NGAL), chitin...

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Sleep Overlap Syndrome

Overlap syndrome, which is known as the coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), was first defined by Flenley. Although it can refer to concomitant occurrence of any of the pulmonary diseases and OSA, overlap syndrome is commonly considered as the coexistence of OSA and COPD. This disease has unique adverse health consequences distinct from ...

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Inflammatory biomarkers in asthma-COPD overlap syndrome

BACKGROUND The clinical phenotypes and underlying mechanisms of asthma-COPD overlap syndrome (ACOS) remain elusive. This study aimed to investigate a comparison of COPD patients with and without ACOS, focusing on inflammatory biomarkers, in an outpatient COPD cohort. METHODS We conducted a cross-sectional study analyzing prospectively collected data from the Ishinomaki COPD Network registry. ...

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Sputum cell count: biomarkers in the differentiation of asthma, COPD and asthma–COPD overlap

INTRODUCTION Cell count in induced sputum is a noninvasive biomarker to assess airway inflammation phenotypes. Accordingly, sputum cell counts are extensively used in the treatment of asthma and COPD. Nevertheless, the clinical application of sputum cell counts in patients with asthma-COPD overlap (ACO) remains elusive. The aim of this study was to investigate sputum cell counts in patients wit...

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ژورنال

عنوان ژورنال: International Journal of Chronic Obstructive Pulmonary Disease

سال: 2017

ISSN: 1178-2005

DOI: 10.2147/copd.s138685